Courses:

Medical Computing >> Content Detail



Study Materials



Readings





Amazon logo When you click the Amazon logo to the left of any citation and purchase the book (or other media) from Amazon.com, MIT OpenCourseWare will receive up to 10% of this purchase and any other purchases you make during that visit. This will not increase the cost of your purchase. Links provided are to the US Amazon site, but you can also support OCW through Amazon sites in other regions. Learn more.




The following text is required for the course and is referenced in the calendar of readings listed in the table below. Amazon logo Shortliffe, E. H., L. E. Perreault, G. Wiederhold, and L. M. Fagan. Medical Informatics: Computer Applications in Health Care and Biomedicine . 2nd ed. New York, NY: Springer, 2003. ISBN: 9780387984728.


LEC #TOPICSREADINGS
1Introduction: Nature of Modern Medicine and Medical Practice Read Chapters 1 & 2 of Shortliffe.
2Nature of Medical Data: Where it is and Where it is NotRead Chapters 9 & 10 of Shortliffe.
3Genomics in Medicine: Centrality of Bioinformatics

"Initial Sequencing and Analysis of the Human Genome." International Human Genome Sequencing Consortium, 409 (2001): Macmillan Magazines Ltd.

Chakravarti, Aravinda. "Population Genetics — Making Sense Out of Sequence." Nature Genetics Supplement 21 (Jan 1999): Ohio: Department of Genetics and Center for Human Genetics, Case Western Reserve University School of Medicine and University Hospitals of Cleveland.

Brown, Patrick O., and David Botstein. "Exploring the New World of the Genome with DNA Microarrays." Nature Genetics Supplement 21 (Jan 1999): Stanford , California : Departments of Biochemistry and Genetics, and the Howard Hughes Medical Institute, Stanford University School of Medicine.

"Distinct Types of Diffuse Large B-cell Lymphoma Identified by Gene Expression Profiling." Nature 403 (3 Feb. 2000): Macmillan Magazines Ltd.

4Patient IdentificationFellegi, Ivan P., and Allen B. Sunter. "A Theory for Record Linkage." Journal of American Statistical Association 64 (328) (Dec 1969): 1183-1210.
5Countering Bioterrorism Chapter 11 of Shortliffe.
6Workflow, Decision Support and Data Gathering

Mueller, Ganslandt, Frankewitsch, Krieglstein, Senninger, and Prokosch. "Workflow Analysis and Evidence-Based Medicine: Towards Integration of Knowledge-Based Functions in Hospital Information Systems." Germany: University of Muenster.

Coiera, Enrico. "Clinical Communication: A New Informatics Paradigm." Jamia (1996): UK.

Coiera, Enrico. "When Conversation is Better than Computation." Jamia (14 Jan. 2000): Washington DC.

Kohane, Isaac S., Philip Greenspun, James Fackler, Christopher Cimino, and Peter Szolovits. "Application of Technology in Building National Electronic-Medical Record Systems via the World Wide Web." Journal of the American Medical Informatics Association 3 (3) (May/Jun 1996).

7Computing Support for the Enterprise
8Diagnosis, Standards, CodificationChapters 6, 12 and 14 of Shortliffe.
9Patient Data Confidentiality and Security

Chapter 7 of Shortliffe.

Barrows, Randolph. C. Jr., Paul D. Clayton. "Privacy Confidentiality and EMR." Journal of the American Medical Informatics Association 3 (2) (Mar/Apr 1996).

Optional

  • For the Record. Protecting Electronic Health Information. Washington D.C. : National Academy Press, 1997.
10Decreasing Variability in Health Care
11Computerized Physician Order Entry: Using Technology To Improve Patient Safety
12Integration and Data Sharing or Medical Data for Quality Improvement
13TelemedicineChapter 14 of Shortliffe.
14Genomic Medicine I: Population Genetics in the Post Genomic Era

Lander, Eric S. "Array of hope." Nature Genetics Supplement  21 (1999): Cambridge, Massachusetts: America Inc.

------., and Nicholas J. Schork. "Genetic Dissection of Complex Traits." Science, New Series, 265 (5181) (30 Sep. 1994): 2037-2048.

"Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome." Science 280 (15 May 1998): 1077.
http://www.sciencemag.org

15Genomic Medicine II: Expression Arrays, Gene Clustering and Distance Metrics Michael, P. S. Brown, William Noble Grundy, David Lin, Nello Cristianini, Charles Walsh Sugnet, Terence S. Furey, Manuel Ares, Jr., and David Haussler. "Knowledge-based Analysis of Microarray Gene Expression Data by Using Support Vector Machines." PNAS 97 (1) (4 Jan. 2000): 262-267.
16Decision Analysis and Decision Support

Chapters 15 and 16 of Shortliffe.

Szolovits, P. "Uncertainty and Decisions in Medical Informatics." Methods of Information in Medicine 34 (1995): 111–21.

17Getting to Causality in Functional Genomics

"The Transcriptional Program in the Response of Human Fibroblasts to Serum." Science 283 (1 Jan. 1999).
www.sciencemag.org

Ramoni, Marco F., Paola Sebastiani, and Isaac S. Kohane. "Cluster Analysis of Gene Expression Dynamics." PNAS. Edited by Louis M. Kunkel.

18Advanced Expert Systems Chapters 12 and 13 of Shortliffe.
19Patient Monitoring
20Genomic Medicine III: Introduction to Genomics
21Genomic Medicine IV: Linking Genotypes and Phenotypes
22Genomic Medicine V: Reverse Engineering Zoltan. "The Perils and Promises of Massively Parallel Biology." Chap. 5 in Genetic Network Analysis, 2002: pp. 23.
23Student Presentations
24Student Presentations
25Student Presentations
26Student Presentations
 


 



 








© 2017 CourseTube.com, by Higher Ed Media LLC. All Rights Reserved.