| SES # | TOPICS | KEY DATES |
|---|---|---|
| 1 | Introduction: The Pharmaceutical Industry and the Drug Development Process Instructors: Stan N. Finkelstein, M.D., Robert H. Rubin, M.D., Anthony J. Sinskey, Ph.D. | |
| 2 | Basic Science Part I – Discovery Innovation and Emerging Technologies, Basic Business Instructor: Anthony J. Sinskey, Ph.D. Guest Lecturer: Robert Mulroy, President and CEO, Merrimack Pharmaceuticals | |
| 3 | Examples of Druggability Issues in the Pharmaceutical Industry Guest Lecturer: Frank Douglas, Ph.D. FDA Drug Regulatory Process Instructor: Stan N. Finkelstein, M.D. | |
| 4 | Basic Science Part II – Molecular Toxicology in Preclinical Studies Instructor: Anthony J. Sinskey, Ph.D. | Teams formed Break into groups and kick-off work on course project |
| 5 | Pharmaceutical Manufacturing Part I Instructor: Charles L. Cooney, Ph.D. | |
| 6 | Pharmaceutical Manufacturing Part II Guest Lecturer: G. K. Raju, Ph.D. | |
| 7 | Clustering Effects in Biotech Companies, Organization and Management Instructor: Thomas J. Allen, Ph.D. Speeding up Information Management in Clinical Practice Guest Lecturer: Zak Kohane, HMS Influenza Guest Lecturer: Adam Tomasi, MBA Candidate, MIT Sloan School of Management | |
| 8 | Valuing Pharmaceutical and Biotech Companies Guest Lecturer: Terrence W. Norchi, M.D., MBA, Former Senior Equity Analyst and Portfolio Manager, Putnam Securities Policy and Economic Considerations in Drug Development Instructor: Stan Finkelstein, M.D. | Project outlines due |
| 9 | Putting it all Together: A System Dynamics Model of the Anti-cholesterol Drugs Market Instructor: Charles L. Cooney, Ph.D. Guest Lecturer: Henry B. Weil, M.S. Analyzing the Human Genome Project Guest Lecturer: Fiona Murray, Ph.D. | |
| 10 | Development and Impact of Genetic Tests Instructor: Jessica Lang-Kosa, Ph.D., MIT Postdoctoral Fellow, POPI Supply Chain Management in the Pharmaceutical Industry Guest Lecturer: David Simchi-Levi, Ph.D. | |
| 11 | The Impact of Pedigree on Drug Supply Chains Guest Lecturer: Daniel W. Engels, Ph.D., Director, HRI The Biotech Disruption to Anti-Cancer Drug Development Guest Lecturer: Lourdes Sosa, Ph.D. Candidate, Sloan School, TIE Program | |
| 12 | Global Health and the Pharmaceutical Industry in 3rd World Countries Instructor: Robert H. Rubin, M.D. Guest Lecturers: John Swen, Alexander Fleming | Microsoft® PowerPoint® presentations due |
| 13 | Student Presentations | Selected project presentations delivered in class |
| Exam Week | Papers due |